Company Filing History:
Years Active: 2013
Title: Innovations of Manu Kohli in HIV Research
Introduction
Manu Kohli is a notable inventor based in Dunn Loring, Virginia, who has made significant contributions to the field of medical research, particularly in the fight against viral infections such as HIV. His innovative approach has led to the development of a unique method that holds promise for therapeutic interventions.
Latest Patents
Kohli holds a patent for "Methods of inhibiting HIV infectivity." This patent describes a method for identifying host genes and encoded proteins that serve as potential targets for therapeutic intervention. The technique employs a Gene Search Vector, which can be either lentivirus or MMLV-based, allowing researchers to interrogate an entire cell genome without prior knowledge of the genomic sequence. This Random Homozygous Gene Perturbation (RUGP) technique is rapidly verifiable and is instrumental in identifying potential host targets for intervention against influenza, HIV, and other viral infections. Notably, the use of Thermal Asymmetric Interlaced (TAIL)-PCR significantly reduces the period for identifying promising targets from months to weeks or less. Specific targets, including PTCH1, Robo1, and Nedd4, are reviewed in detail within the patent.
Career Highlights
Kohli's work at Functional Genetics, Inc. has positioned him at the forefront of genetic research. His innovative methods have the potential to revolutionize how researchers approach viral infections, making significant strides in the field of therapeutic interventions.
Collaborations
Kohli has collaborated with esteemed colleagues such as Michael Scott Kinch and Michael Goldblatt, further enhancing the impact of his research through shared expertise and knowledge.
Conclusion
Manu Kohli's contributions to the field of HIV research through his innovative patent demonstrate his commitment to advancing medical science. His work not only provides valuable insights into viral infections but also paves the way for future therapeutic developments.