Company Filing History:
3 out of 3 
1 out of 1 
1 out of 1 Years Active: 2019-2024
Title: Manson Fok: Innovator in Biologics
Introduction
Manson Fok is a prominent inventor based in Hong Kong, known for his significant contributions to the field of biologics. He holds a total of five patents, showcasing his innovative approach to medical science and therapeutic development.
Latest Patents
Among his latest patents is a method for preparing a pegylated human IL-11 composition. This method involves producing a PEGylated interleukin 11 (IL-11) by treating a recombinant IL-11 with an equimolar to low molar excess of PEG carrying an amine-reactive group. This process results in a highly pure monoconjugate preparation that improves the half-life in serum while maintaining desirable therapeutic activity and reducing side effects. Notably, the IL-11 is often an N-terminally truncated human or humanized IL-11, featuring a 20 Kd or 40 Kd branched PEG moiety, which enhances stability in serum and sustains biological activity.
Another significant patent involves systems and methods for the production of recombinant IL-11 in yeast. In this process, recombinant interleukin-11 (rhIL-11) is expressed in yeast and isolated from aerobic fermentation media through a series of purification steps. The resulting highly purified rhIL-11 exhibits high biological activity and low levels of dimer and oxidized rhIL-11.
Career Highlights
Manson Fok has worked with notable companies such as Nansha Biologics Limited and Nansha Biologies Limited, where he has applied his expertise in the development of biologic therapies. His work has significantly advanced the understanding and application of interleukin-11 in therapeutic contexts.
Collaborations
Throughout his career, Manson has collaborated with esteemed colleagues, including Qui-Lim Choo and Johnson Yiu-Nam Lau. These partnerships have contributed to the successful development of his innovative projects.
Conclusion
Manson Fok's contributions to the field of biologics through his patents and collaborations highlight his role as a leading inventor in medical science. His work continues to influence the development of effective therapeutic solutions.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.