Manoj Samuel

Title: Innovations by Inventor Manoj Samuel

Introduction

Manoj Samuel is an accomplished inventor based in West Chester, PA (US). He has made significant contributions to the field of biotechnology, particularly in DNA manipulation techniques. With a total of 2 patents, his work has paved the way for advancements in genetic research and applications.

Latest Patents

Manoj Samuel's latest patents include innovative methods for chain reaction cloning using a bridging oligonucleotide and DNA ligase. This method allows for the ligation of double-stranded DNA molecules by utilizing DNA ligases and bridging oligonucleotides. The process involves denaturing double-stranded nucleic acid molecules into single-stranded forms, which are then aligned correctly using a template. DNA ligase plays a crucial role in joining these single-stranded nucleic acid molecules into a larger composite molecule. The applications of this technology are vast, including site-specific ligation of DNA fragments generated by various methods such as restriction enzyme digestion and PCR amplification. Additionally, he has developed methods for detecting the presence and measuring the quantity of linear DNA in samples containing circular DNA, utilizing ATP-dependent enzymes.

Career Highlights

Manoj Samuel is currently employed at American Home Products Corporation, where he continues to innovate and contribute to the field of biotechnology. His work has garnered attention for its practical applications in genetic research and diagnostics.

Collaborations

Some of his notable coworkers include C Satishchandran and Catherine Julia Pachuk, who have collaborated with him on various projects within the company.

Conclusion

Manoj Samuel's contributions to biotechnology through his patents and innovative methods have significantly impacted the field. His work exemplifies the importance of innovation in advancing scientific research and applications.