Manoj Hariharan

Title: Innovations by Manoj Hariharan in HIV Research

Introduction

Manoj Hariharan is a notable inventor based in Delhi, India. He has made significant contributions to the field of biomedical research, particularly in the area of HIV. His work focuses on the identification of human microRNA targets within the HIV genome, which has potential therapeutic implications.

Latest Patents

Manoj Hariharan holds a patent titled "Human microRNA targets in HIV genome and a method of identification thereof." This invention relates to the discovery of six human microRNAs that target specific genes in the HIV genome, including vpr, env, and vif. The identified microRNAs are hsa-miR-29a, hsa-miR-29b, hsa-miR-29c, hsa-mir-149, hsa-mir-324-5p, and hsa-mir-378. These microRNAs or their homologues can potentially be used as therapeutics against HIV infection. The invention also presents a novel strategy to target HIV-1 genes using human microRNAs to inactivate or block HIV activity. The computational approach for identifying these targets has been validated through experimental methods.

Career Highlights

Manoj Hariharan is associated with the Council of Scientific and Industrial Research, where he conducts his research. His work has garnered attention for its innovative approach to tackling HIV, a global health challenge.

Collaborations

Some of his notable coworkers include Samir Kumar Brahmachari and Vinod Scaria, who have also contributed to advancements in biomedical research.

Conclusion

Manoj Hariharan's innovative work in identifying microRNA targets in the HIV genome represents a significant step forward in the search for effective treatments against HIV infection. His contributions to science and research continue to inspire advancements in the field.