Company Filing History:
Years Active: 2019-2025
Title: Manjula Karpurapu: Innovator in Peptide Research
Introduction
Manjula Karpurapu is a distinguished inventor based in Columbus, OH (US). She has made significant contributions to the field of peptide research, particularly in the development of inhibitors that target specific protein interactions. With a total of 3 patents to her name, her work is paving the way for advancements in therapeutic applications.
Latest Patents
One of her latest patents focuses on "Peptidyl inhibitors of calcineurin-NFAT interaction." This patent describes peptides and peptide conjugates that comprise calcineurin binding motifs (CNBM) which inhibit the interaction between calcineurin and NFAT. The invention includes various embodiments where the peptides may contain a hydrophobic, non-peptidic moiety (RH) that interacts with the hydrophobic pocket on a calcineurin protein. The sequences involved are designed to enhance the efficacy of these inhibitors, showcasing her innovative approach to peptide design.
Career Highlights
Manjula Karpurapu is affiliated with the Ohio State Innovation Foundation, where she continues to push the boundaries of peptide research. Her work has garnered attention for its potential applications in medical therapies, particularly in conditions where calcineurin-NFAT interactions play a critical role.
Collaborations
Throughout her career, she has collaborated with notable colleagues such as Dehua Pei and John W. Christman. These partnerships have contributed to her research and the successful development of her patented technologies.
Conclusion
Manjula Karpurapu is a pioneering inventor whose work in peptide research is making a significant impact in the field. Her innovative patents and collaborations highlight her commitment to advancing scientific knowledge and therapeutic solutions.