Location History:
- Andhra Pradesh, IN (2010)
- Hyderabad, IN (2013)
Company Filing History:
Years Active: 2010-2013
Title: Mandapati Jayalakshmi: Innovator in Biosensor Technology
Introduction
Mandapati Jayalakshmi is a notable inventor based in Hyderabad, Telangana, India. He has made significant contributions to the field of biosensor technology, holding two patents that showcase his innovative approach to health monitoring.
Latest Patents
His latest patents include a potentiometric cholesterol sensor designed for the quantitative estimation of total cholesterol in human blood serum. This invention provides a novel sensor that utilizes a molecular imprint of cholesterol, allowing for accurate cholesterol measurement in the range of 150-250 mg/dl. The sensor device is fabricated using an Ion Selective Field Effect Transistor (ISFET) coated with a molecular imprint of cholesterol on the dielectric gate. This innovative sensing material demonstrates specific selectivity towards cholesterol, even in the presence of other organic constituents in human blood serum.
Another significant patent is a biosensor developed to determine potassium concentration in human blood serum. This invention employs dibenzo-18-crown-6 (DB18C6) as an ionophore, which exhibits excellent selectivity towards potassium, despite the presence of sodium at much higher concentrations. The biosensor is characterized by an ISFET coated with a monolayer of crown ether, dissolved in chloroform, on the gate of the electrode. This technology is crucial for accurately measuring potassium levels, which are typically found in ppm levels ranging from 137 to 200 mg/litre.
Career Highlights
Mandapati Jayalakshmi is affiliated with the Council of Scientific & Industrial Research, where he continues to advance his research in biosensor technology. His work has the potential to significantly impact medical diagnostics and health monitoring.
Collaborations
He has collaborated with notable coworkers, including Sunkam Vanaja and Sunkara Sakunthala Madhavendra, contributing to the development of innovative biosensing technologies.
Conclusion
Mandapati Jayalakshmi's contributions to biosensor technology highlight his role as an influential inventor in the field. His patents reflect a commitment to improving health diagnostics through innovative sensor design.