Company Filing History:
Years Active: 1991-1994
Title: Man S Yu: Innovator in Pharmaceutical Solvent Systems
Introduction
Man S Yu is a notable inventor based in Rochester, NY (US), recognized for his contributions to the field of pharmaceuticals. He holds 2 patents that focus on enhancing the solubility of pharmaceutical agents, which is crucial for improving drug delivery and bioavailability.
Latest Patents
One of his latest patents involves a solvent system designed to enhance the solubility of acidic, basic, or amphoteric pharmaceutical agents. This innovative system produces a highly concentrated solution suitable for softgel filling or two-piece encapsulation. The solvent system comprises polyethylene glycol containing 0.2-1.0 mole equivalents of an ionizing agent per mole equivalent of the pharmaceutical agent and 1-20% water. Additionally, glycerin or polyvinylpyrrolidone may be added to further enhance the solubility of certain drugs. The disclosed solvent system is capable of enhancing the solubility of pharmaceutical agents by 40-400%. The ionizing agent functions by causing partial ionization of the free pharmaceutical agent, which is essential for improving bioavailability. This system not only facilitates the delivery of pharmaceutical agents already in solution but also allows for encapsulation in a small vessel, making it easier to swallow. Furthermore, the concentrated solutions can be converted into tablets and used in veterinary applications.
Career Highlights
Man S Yu is currently associated with R.P. Scherer Corporation, where he continues to innovate in the pharmaceutical sector. His work focuses on developing solutions that enhance drug solubility and bioavailability, which are critical for effective treatment options.
Collaborations
Some of his notable coworkers include Foo S Hom and Sibaprasanna Chakrabarti, who contribute to the collaborative efforts in advancing pharmaceutical technologies.
Conclusion
Man S Yu's innovative work in developing solvent systems for pharmaceuticals significantly impacts drug delivery and patient care. His contributions are vital for enhancing the effectiveness of various pharmaceutical agents.