Location History:
- Kyungsangbuk-do, KR (2007)
- Pohang-si, KR (2011)
Company Filing History:
Years Active: 2007-2011
Title: Innovations by Man Ki Song
Introduction
Man Ki Song is a notable inventor based in Pohang-si, South Korea. He has made significant contributions to the field of biotechnology, particularly in the development of DNA vaccine adjuvants. With a total of 2 patents, his work focuses on enhancing immune responses against various diseases.
Latest Patents
One of his latest patents involves the genes of the IL-12P40 subunit mutated to improve the activity of IL-12. This invention relates to a mutant gene capable of producing IL-12 (interleukin 12) of both human and mouse origin with high activity. The expression vector that includes this mutant gene is designed for use as a DNA vaccine adjuvant. Specifically, the IL-12P40 mutant gene inhibits the secretion of IL-12P40 while normally secreting active IL-12P70. This is achieved by mutating the Asn-222 (human) or Asn-220 (mouse) amino acid of IL-12P40, which acts as a competitive inhibitor of the active form of IL-12, IL-12P70. The implications of this invention are significant, as it can be utilized for DNA vaccination and gene therapy against various diseases, including AIDS, hepatitis C, hepatitis B, cancer, influenza, tuberculosis, and malaria.
Career Highlights
Man Ki Song is currently associated with Genexine Co., Ltd., where he continues to innovate in the field of biotechnology. His work has been instrumental in advancing the understanding and application of DNA vaccines.
Collaborations
He collaborates with notable colleagues such as Young Chul Sung and Sung Hee Lee, contributing to a dynamic research environment that fosters innovation.
Conclusion
Man Ki Song's contributions to biotechnology, particularly through his patents on IL-12P40 subunit mutations, highlight his role as a key inventor in the field. His work has the potential to significantly impact the development of effective treatments for various diseases.