Malene Jackerott

Title: Malene Jackerott: Innovator in Antisense Oligonucleotides

Introduction

Malene Jackerott is a notable inventor based in Horsholm, Denmark. She has made significant contributions to the field of biotechnology, particularly in the development of antisense oligonucleotides. With a total of three patents to her name, her work focuses on innovative solutions for medical challenges.

Latest Patents

One of her latest patents involves the use of oligonucleotides for the reduction of PD-L1 expression. This invention relates to antisense oligonucleotides that can effectively reduce the expression of PD-L1 in target cells. The oligonucleotides are designed to hybridize with PD-L1 mRNA, providing a targeted approach to treatment. Furthermore, the invention includes conjugates of the oligonucleotide and pharmaceutical compositions aimed at treating various viral liver infections, such as HBV, HCV, and HDV. It also addresses parasite infections like malaria, toxoplasmosis, leishmaniasis, and trypanosomiasis, as well as liver cancer and metastases in the liver.

Career Highlights

Malene Jackerott is currently employed at Hoffmann-La Roche Inc., where she continues to advance her research and development efforts. Her work has garnered attention in the scientific community, contributing to the understanding and treatment of complex diseases.

Collaborations

Throughout her career, Malene has collaborated with esteemed colleagues, including Lykke Pedersen and Hassan Javanbakht. These partnerships have enhanced her research and expanded the impact of her inventions.

Conclusion

Malene Jackerott stands out as an innovative inventor in the field of biotechnology, particularly with her advancements in antisense oligonucleotides. Her contributions are paving the way for new treatments in medicine, showcasing the importance of innovation in addressing health challenges.