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1 out of 832,812 Years Active: 2003-2018
Title: The Innovative Contributions of Malcolm J Fraser
Introduction
Malcolm J Fraser, an esteemed inventor located in Granger, IN, is known for his significant contributions to the field of biotechnology. With a portfolio of five patents, Fraser is recognized for his cutting-edge work in transformation methods and glycoprotein production, significantly advancing genetic research and applications.
Latest Patents
His latest patents include "Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector piggyBac." This invention presents a novel method for transforming insect genomes, achieving a much-enhanced transformation frequency. The vectors and plasmids described in this patent include minimal nucleotide sequences homologous to essential regions of the native piggyBac nucleic acid sequence. This innovative approach allows for the development of transgenic organisms, with transformation frequencies improved by a factor of 100 or more compared to other methods. Additionally, Fraser was involved in developing a "Transgenic silkworm system for recombinant glycoprotein production." This system provides a scalable platform for the production of human glycosylated proteins using silkworms, showcasing his versatility and innovation in biotechnology.
Career Highlights
Malcolm J Fraser has had a notable career, contributing his expertise at the University of Notre Dame Du Lac among other institutions. His work has not only pushed the boundaries of genetic transformation techniques but also opened new avenues for producing complex proteins essential for various biological applications.
Collaborations
Throughout his career, Fraser has collaborated with notable coworkers such as Xu Li and Paul D Shirk. These collaborations have fostered innovation and have been instrumental in advancing the research he is known for today.
Conclusion
Malcolm J Fraser's contributions through his inventive patents have made substantial impacts on the field of biotechnology. His pioneering methods for genetic transformation and glycoprotein production continue to influence research and applications, solidifying his reputation as a distinguished inventor in Granger, IN.