Company Filing History:
3 out of 1,012 
2 out of 11 Years Active: 1994-1999
Title: The Innovations of Makoto Yaguchi
Introduction
Makoto Yaguchi is a prominent inventor based in Ottawa, Canada. He has made significant contributions to the field of enzymology, particularly in the modification of xylanase enzymes. With a total of 5 patents, his work has advanced the understanding and application of these enzymes in various industrial processes.
Latest Patents
Yaguchi's latest patents focus on the modification of xylanase to improve thermophilicity and alkalophilicity. One of his notable inventions is a modified xylanase of Family 11 that demonstrates enhanced thermophilicity, alkalophilicity, and thermostability compared to natural xylanase. The modifications include changing specific amino acids in Trichoderma reesei xylanase II and substituting amino acids in the N-terminal region with those from other xylanase enzymes. Additionally, he has explored the extension of the N-terminus with specific tripeptides to further improve enzyme performance.
Career Highlights
Throughout his career, Yaguchi has worked with esteemed organizations such as the National Research Council of Canada and Her Majesty the Queen in Right of Canada, as represented by the National Research Council. His research has been pivotal in enhancing the efficiency of xylanase enzymes, which are crucial in the pulp and paper industry.
Collaborations
Yaguchi has collaborated with notable colleagues, including Wing L Sung and Kazuhiko Ishikawa. These partnerships have contributed to the successful development and application of his patented technologies.
Conclusion
Makoto Yaguchi's innovative work in the field of xylanase modification has led to significant advancements in enzyme performance. His contributions continue to impact various industries, showcasing the importance of innovation in scientific research.