This inventor holds 2 USPTO granted patents and 3 published patent applications. Top assignee: Kyoto University. Active years: 2026.
Company Filing History:
Years Active: 2026
Title: Makoto Ryosaka: Innovator in Ureteric Bud Research
Introduction
Makoto Ryosaka is a prominent inventor based in Kyoto, Japan. He has made significant contributions to the field of regenerative medicine, particularly in the study of ureteric bud cells. With a total of 2 patents, his work focuses on innovative methods for isolating and inducing ureteric bud-like tissues.
Latest Patents
Ryosaka's latest patents include a method for isolating ureteric bud tip cells. This method involves contacting cells, tissues, or organoids containing ureteric bud tip cells with a very low density lipoprotein receptor (VLDL-R) binding agent. The binding agent serves as an indicator for isolating the ureteric bud tip cells. Another significant patent is a method for inducing ureteric bud-like tissue from pluripotent stem cells, specifically iPS and ES cells. This method outlines a system for producing ureteric bud-like tissue through various stages of differentiation, including anterior primitive streak cells, anterior intermediate mesoderm cells, and Wolffian duct cells. Additionally, it provides methods for maintaining ureteric bud-like organoids and for expanding ureteric bud-like tip tissue.
Career Highlights
Makoto Ryosaka is affiliated with Kyoto University, where he conducts his research and development. His work has garnered attention for its potential applications in regenerative medicine and tissue engineering.
Collaborations
Ryosaka collaborates with notable colleagues such as Shinichi Mae and Kenji Osafune, contributing to advancements in their shared field of research.
Conclusion
Makoto Ryosaka's innovative research in ureteric bud cells positions him as a key figure in regenerative medicine. His patents reflect a commitment to advancing scientific knowledge and practical applications in this vital area of study.