Makoto Ogura

Title: Makoto Ogura: Innovator in Tissue-Based Diagnosis

Introduction

Makoto Ogura is a prominent inventor based in Ryugasaki, Japan. He has made significant contributions to the field of tissue-based diagnosis, holding a total of 6 patents. His innovative work focuses on methods and systems that enhance the diagnosis and evaluation of various diseases through advanced tissue analysis.

Latest Patents

Ogura's latest patents include groundbreaking methods for tissue-based diagnosis. One of his inventions provides methods and compositions that involve applying energy to a tissue of interest. This process generates a liquefied sample comprising tissue constituents, allowing for rapid tissue sampling and qualitative or quantitative detection of analytes. These analytes may include various biomolecules, drugs, and microbes. The determination of tissue composition can be utilized in numerous applications, such as diagnosing local and systemic diseases, evaluating the bioavailability of therapeutics, forensic detection of drugs-of-abuse, and assessing changes in the tissue microenvironment after exposure to harmful agents.

Another notable patent is a system, method, and devices for tissue-based diagnosis. This invention discloses kits designed to partially liquefy tissue. The kit includes a liquefaction promoting medium (LPM) that may consist of a non-ionic surfactant, a zwitterionic surfactant, and an abrasive material. The kit also contains instructions for treating the tissue of a living subject by applying the LPM and abrasive material, followed by transmitting energy to the tissue to facilitate partial dissolution of its components.

Career Highlights

Throughout his career, Ogura has worked with esteemed institutions, including the University of California. His research and inventions have significantly advanced the field of tissue diagnostics, making him a key figure in medical innovation.

Collaborations

Ogura has collaborated with notable professionals in his field, including Samir M Mitragotri and Sumit Paliwal. These collaborations have further enriched his research and contributed to the development of his innovative patents.

Conclusion

Makoto Ogura's contributions to tissue-based diagnosis exemplify the impact of innovation in medical technology. His patents not only enhance diagnostic capabilities but also pave the way for future advancements in healthcare.