Chiba, Japan

Makoto Hirayama


Average Co-Inventor Count = 6.5

ph-index = 1

Forward Citations = 3(Granted Patents)


Company Filing History:


Years Active: 1987-1989

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4 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Makoto Hirayama

Introduction: Makoto Hirayama, an accomplished inventor based in Chiba, Japan, has made significant contributions to the field of chemical inventions. With a total of four patents to his name, he has focused on developing compounds that hold immense potential for the pharmaceutical industry, particularly in creating effective heart drugs.

Latest Patents: Hirayama's latest patents include innovative cyclohexanone derivatives. One notable invention involves pyridyl-cyclohexanone compounds, which are represented by a specific general formula that allows for variations in substituent R, encompassing hydrogen or an acetyl group. These derivatives serve as crucial intermediates in the production of isoquinoline derivatives, which are vital for medicinal applications. Additionally, another patent showcases an isoquinoline derivative with a designated formula, where substituents can vary widely, offering a range of therapeutic applications with low toxicity and high safety, especially as cardiotonic medications.

Career Highlights: Hirayama's career has been characterized by his dedication to chemical innovation. His work at Mitsui Toatsu Chemicals, Incorporated has positioned him at the forefront of research in creating effective medicinal compounds. His inventions contribute to advancements in drug development, particularly those targeting cardiovascular health.

Collaborations: Throughout his career, Hirayama has collaborated with notable colleagues, including Masahiko Maruyama and Takafumi Kitano. Their combined expertise has fostered an environment conducive to groundbreaking discoveries in chemical compounds used in pharmaceuticals.

Conclusion: Makoto Hirayama exemplifies the innovative spirit of modern inventors. His contributions to the field of chemistry through his patents and collaborative efforts signify the potential for advancements in drug development, particularly for heart-related medications. As the industry continues to evolve, Hirayama's work remains a vital part of the ongoing quest for effective therapeutic solutions.

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