Lawrenceville, NJ, United States of America

Madelene M Antane


Average Co-Inventor Count = 4.3

ph-index = 4

Forward Citations = 75(Granted Patents)


Location History:

  • Lawrenceville, NJ (US) (1995 - 2002)
  • West Windsor, NJ (US) (2004 - 2009)

Company Filing History:


Years Active: 1995-2009

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15 patents (USPTO):Explore Patents

Title: The Innovative Journey of Madelene M Antane

Introduction

Madelene M Antane is an accomplished inventor based in Lawrenceville, NJ. With a remarkable portfolio that includes 15 patents, her work significantly contributes to the field of organic chemistry and pharmaceutical development. Antane's innovations focus on the selective synthesis of enantiomers and other complex compounds, showcasing her expertise in this specialized area.

Latest Patents

Among her latest patents, Antane developed a process for the selective synthesis of enantiomers of substituted 1-(2-amino-1-phenyl-ethyl)-cyclohexanols. This innovative method allows for the enantioselective synthesis of (S)- or (R)-1-[2-dimethylamino)-1-(methoxyphenyl)ethyl]cyclohexanol and its analogues or salts. The detailed steps involved include reacting oxazolidinones with mixed anhydrides, treating them with aprotic amines and titanium chloride, and performing various hydrolysis and reduction processes, culminating in the production of chiral acids and amides.

Another notable contribution involves the synthetic methods for preparing 6-alkyl-5-arylsulfonyl-dihydrophenanthridines. These methods aim for the production of specific compounds, offering new pathways for drug development and chemical applications.

Career Highlights

Madelene has had a significant career, working with major corporations such as American Home Products Corporation and Wyeth. Her experiences in these organizations have allowed her to deepen her expertise in pharmaceutical processes and contribute to various innovative projects in the field.

Collaborations

Throughout her career, Antane has collaborated with talented individuals, including John Anthony Butera and Bradford H. Hirth. These collaborations have fostered an environment of creativity and knowledge sharing, further enhancing the impact of her work in the industry.

Conclusion

Madelene M Antane stands out as a pioneering inventor whose work in the field of chemistry and synthesis has paved the way for new developments in pharmaceutical applications. Her 15 patents reflect her dedication to innovation and her ability to push the boundaries of what is possible in her field. Antane's contributions not only advance scientific understanding but also inspire future generations of inventors and researchers.

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