Madeleine Durbeej

Title: The Innovative Contributions of Madeleine Durbeej

Introduction

Madeleine Durbeej is a prominent inventor based in Iowa City, IA (US). She has made significant contributions to the field of cardiomyopathy research. Her work focuses on the genetic underpinnings of this condition, which affects the heart muscle.

Latest Patents

Durbeej holds a patent related to the pathogenesis of cardiomyopathy. This patent describes a mouse model that is homozygous for a disrupted δ-sarcoglycan gene. The disruption prevents the synthesis of functional δ-sarcoglycan in the cells of the mouse, leading to a reduced amount of β- and ε-sarcoglycan and sarcospan. Additionally, it results in a disruption of the sarcoglycan-sarcospan complex in the smooth muscle of the mouse. Furthermore, the patent also covers a mouse model homozygous for a disrupted β-sarcoglycan gene, which similarly affects the synthesis of functional β-sarcoglycan.

Career Highlights

Durbeej is affiliated with the University of Iowa Research Foundation, where she conducts her research. Her innovative work has garnered attention in the scientific community, particularly for its implications in understanding cardiomyopathy.

Collaborations

Some of her notable coworkers include Kevin P. Campbell and Ramon Coral. Their collaborative efforts contribute to advancing research in the field of cardiomyopathy.

Conclusion

Madeleine Durbeej's contributions to the understanding of cardiomyopathy through her innovative research and patent are invaluable. Her work continues to pave the way for future advancements in this critical area of health.