Lynn P Nelles

Title: Lynn P Nelles: Innovator in Biochemical Purification Processes

Introduction

Lynn P Nelles is a prominent inventor based in Bartlesville, OK (US). She has made significant contributions to the field of biochemical purification, holding a total of 2 patents. Her work focuses on innovative methods for purifying complex biological substances, which have important applications in biotechnology and medicine.

Latest Patents

Nelles' latest patents include a large-scale process for the purification of alcohol oxidase and a method for purifying recombinant tumor necrosis factor (TNF). The first patent describes a process for purifying alcohol oxidase from whole cells of Pichia pastoris grown on methanol. This process involves sequential steps of autolysis, crossflow filtration, ultrafiltration, and recrystallization. The second patent outlines a method for purifying recombinant TNF from cultures of microorganisms transformed with vectors that code for TNF production. This method utilizes a sequence of contacting steps, allowing for substantial purification of TNF-containing fermentation broth through a multi-component chromatography system without the need for intermediate isolation or concentration.

Career Highlights

Throughout her career, Lynn P Nelles has worked with notable companies, including Phillips Petroleum Company. Her expertise in biochemical processes has positioned her as a valuable asset in the field of biotechnology.

Collaborations

Nelles has collaborated with various professionals, including Roger G Harrison, Jr., enhancing her research and development efforts in biochemical purification.

Conclusion

Lynn P Nelles is a distinguished inventor whose work in biochemical purification processes has led to significant advancements in the field. Her innovative patents reflect her commitment to improving purification methods, which are crucial for various applications in biotechnology and medicine.