Lyndsey Durose

Title: Innovations of Lyndsey Durose

Introduction

Lyndsey Durose is a prominent inventor based in Abingdon, GB. She has made significant contributions to the field of biotechnology, particularly in the development of fusion proteins. With a total of four patents to her name, Durose's work is at the forefront of innovative solutions in cellular biology.

Latest Patents

One of her latest patents involves a single chain, polypeptide fusion protein. This invention comprises a non-cytotoxic protease or a fragment capable of cleaving a protein of the exocytic fusion apparatus of a target cell. It also includes a Targeting Moiety that binds to a Binding Site on the target cell, which can undergo endocytosis to be incorporated into an endosome within the target cell. Additionally, the fusion protein features a protease cleaving site located between the non-cytotoxic protease and the Targeting Moiety, along with a translocation domain that facilitates the movement of the protease or its fragment from within an endosome across the endosomal membrane into the cytosol of the target cell.

Career Highlights

Lyndsey Durose is currently associated with Syntaxin Limited, where she continues to push the boundaries of scientific research and innovation. Her work has garnered attention for its potential applications in therapeutic interventions and drug delivery systems.

Collaborations

Throughout her career, Durose has collaborated with notable colleagues, including Keith Foster and John Andrew Chaddock. These partnerships have contributed to the advancement of her research and the successful development of her inventions.

Conclusion

Lyndsey Durose's innovative work in the field of fusion proteins exemplifies her commitment to advancing biotechnology. Her contributions are paving the way for future developments in cellular biology and therapeutic applications.