This inventor holds 2 USPTO granted patents. Top assignee: Alpha Therapeutic Corporation. Active years: 1997-1999.
Company Filing History:
Years Active: 1997-1999
Title: Innovations by Lyndon Luz in Protein Purification
Introduction
Lyndon Luz is an accomplished inventor based in Huntington Park, CA (US). He has made significant contributions to the field of protein purification, holding a total of 2 patents. His work focuses on enhancing the yield and purity of important proteins, which has implications in various biomedical applications.
Latest Patents
Lyndon Luz's latest patents include a process for increasing the yield of a protein that has been subjected to purification. This innovative process involves providing an impure protein fraction containing alpha-1-proteinase inhibitor (alpha-1-PI). The method includes suspending the impure protein fraction in an aqueous solution at pH 6, recovering insoluble proteins, and resuspending them in an aqueous solution at pH 8.5. The addition of polyethylene glycol (PEG) precipitates alpha-2 proteins, while zinc chloride (ZnCl2) is used to precipitate crude alpha-1-PI from the PEG supernatant. The crude alpha-1-PI is then resolubilized and applied to an anion-exchange medium, allowing for the recovery of a fraction comprising alpha-1-PI, which has a specific activity of about 1.0 units/OD280.
Another notable patent by Luz is a process for separating alpha-1-proteinase inhibitor from COHN IV1. This process mirrors the previous one, emphasizing the purification of alpha-1-PI from impure protein fractions through similar steps, ensuring high specificity and yield.
Career Highlights
Lyndon Luz is currently employed at Alpha Therapeutic Corporation, where he continues to innovate in the field of protein purification. His expertise and dedication to research have positioned him as a valuable asset in his organization.
Collaborations
Luz has collaborated with notable colleagues, including Duk Sung Hwang and Kazuo Takechi. These partnerships have likely contributed to the advancement of his research and the successful development of his patents.
Conclusion
Lyndon Luz's contributions to protein purification through his innovative patents demonstrate his commitment to advancing scientific knowledge and practical applications in the field. His work at Alpha Therapeutic Corporation and collaborations with esteemed colleagues further highlight his impact on the industry.