Company Filing History:
Years Active: 1981-1987
Title: Lydia Peer: Innovator in Pharmaceutical Chemistry
Introduction
Lydia Peer is a notable inventor based in West Orange, NJ (US). She has made significant contributions to the field of pharmaceutical chemistry, holding a total of 3 patents. Her work focuses on innovative processes that enhance the production of complex chemical compounds.
Latest Patents
One of Lydia's latest patents involves a multistep process for producing (-)-5-[(R)-1-hydroxy-2-((R)-1-methyl-3-phenyl-propyl)aminoethyl]salicylamide in high yields without the need for chromatography. This process is stereoselective, starting with the reaction of D-(+)-alpha-methylbenzylamine with benzylacetone. The resulting Schiff's base undergoes reduction to form an amine as an R,R: R,S diastereomeric mixture. The mixture is then resolved to obtain the R,R stereoisomer as a salt, which is converted to a free base. The R,R free base reacts with an O-protected alpha-bromo-3-carbamoyl-acetophenone to produce the corresponding R,R-ketobenzamide. This is followed by reduction to yield a mixture of S,R,R;R,R,R hydroxybenzamide, removal of the protecting groups, resolution of the deprotected product, and conversion to the free R,R-amine.
Another patent focuses on benzodiazepine intermediates, disclosing a compound formula where X and Y can be independently selected from hydrogen, halogen, trifluoromethyl, nitro, C1 to C6 alkyl, and C1 to C6 alkoxy, while Z is C1 to C6 alkyl or hydrogen.
Career Highlights
Lydia Peer is currently associated with Schering Corporation, where she continues to innovate in the pharmaceutical sector. Her work has been instrumental in developing new methodologies that improve the efficiency and effectiveness of drug production.
Collaborations
Lydia has collaborated with esteemed colleagues such as Esther Babad and Joseph Mayer, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Lydia Peer stands out as a pioneering inventor in pharmaceutical chemistry, with a focus on innovative processes that enhance drug production. Her contributions are significant in advancing the field and improving therapeutic options