Luyan Zhu

Title: Innovations of Luyan Zhu in Blood-Clotting Factor VIII

Introduction

Luyan Zhu is a notable inventor based in Kaifeng, China. He has made significant contributions to the field of biotechnology, particularly in the development of blood-clotting factors. His work focuses on enhancing the efficacy and pharmacokinetics of therapeutic proteins.

Latest Patents

Luyan Zhu holds a patent for a highly glycosylated human blood-clotting factor VIII fusion protein, along with its manufacturing method and applications. This innovative fusion protein comprises a human blood-clotting factor VIII, a flexible peptide connector, at least one rigid unit of a human chorionic gonadotropin β-subunit carboxyl terminal peptide, and a half-life extending portion, preferably selected from a human IgG Fc variant. The fusion protein demonstrates a similar level of biological activity as recombinant factor VIII while extending its in vivo half-life, thereby improving pharmacokinetics and drug efficacy.

Career Highlights

Throughout his career, Luyan Zhu has worked with prominent companies in the pharmaceutical industry. He has been associated with Ampsource Biopharma Shanghai Inc. and Furen Pharmaceutical Group Co., Ltd. His experience in these organizations has contributed to his expertise in developing innovative therapeutic solutions.

Collaborations

Luyan Zhu has collaborated with several professionals in his field, including Qiang Li and Wenchen Zhu. These collaborations have fostered a productive environment for innovation and research in biotechnology.

Conclusion

Luyan Zhu's contributions to the development of blood-clotting factors highlight his role as a significant inventor in the biotechnology sector. His innovative approaches continue to influence the efficacy of therapeutic proteins, showcasing the importance of research and development in healthcare.