This inventor holds 2 USPTO granted patents. Top assignees: New York University, University of Rochester. Active years: 1996-1998.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1996-1998
Title: Innovations of Lung C Chen
Introduction
Lung C Chen is a notable inventor based in Upper Saddle River, NJ (US). He has made significant contributions to the field of pharmacology, particularly in the development of anticholinergic agents. With a total of 2 patents, his work has implications for treating various pulmonary diseases.
Latest Patents
One of Lung C Chen's latest patents focuses on anhydroecogonine compounds and their use as anticholinergic agents. Specifically, Methylecgonidine (MEG), which is produced when cocaine base ('crack') is heated, was tested for its effects on isolated tracheal rings stimulated by acetylcholine. At micromolar concentrations, cocaine was found to sensitize these tracheal rings, enhancing both the potency and efficacy of acetylcholine-induced contraction. Interestingly, MEG, at nanomolar concentrations and above, non-competitively and irreversibly antagonized acetylcholine-induced contraction, independent of cocaine's actions. Additionally, MEG exhibited antihistaminic activity, suggesting its potential use in preventing or treating diseases that can be addressed by antimuscarinic anticholinergic agents, anti-histaminic agents, or spasmolytic agents, particularly in cases of bronchoconstriction associated with pulmonary diseases like asthma.
Career Highlights
Lung C Chen has had a distinguished career, contributing to research and development in pharmacology. His innovative work has led to advancements in understanding the mechanisms of action of various compounds, particularly in relation to respiratory health.
Collaborations
Throughout his career, Lung C Chen has collaborated with esteemed colleagues, including John F Graefe and Jalil Shojaie. These partnerships have further enriched his research and contributed to the advancement of knowledge in his field.
Conclusion
Lung C Chen's contributions to the field of pharmacology, particularly through his patents on anhydroecogonine compounds, highlight his role as an influential inventor. His work continues to pave the way for new treatments in respiratory health.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile