Lafayette, CA, United States of America

Luke S Guo


Average Co-Inventor Count = 2.1

ph-index = 5

Forward Citations = 275(Granted Patents)


Location History:

  • Lafeyette, CA (US) (1993)
  • Lafayette, CA (US) (1989 - 1999)

Company Filing History:


Years Active: 1989-1999

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5 patents (USPTO):Explore Patents

Title: Innovations and Contributions of Inventor Luke S Guo

Introduction

Luke S Guo is a notable inventor based in Lafayette, California. He has made significant contributions to the field of pharmaceuticals, particularly in the development of innovative drug delivery systems. With a total of five patents to his name, Guo's work has had a substantial impact on the treatment of bacterial and fungal infections.

Latest Patents

Among his latest patents is a liposome composition and method for administering a quinolone. This innovative composition is designed for treating bacterial infections and includes liposomes with a surface coating of hydrophilic polymer chains, along with an entrapped drug-conjugate composed of ciprofloxacin conjugated to an amino acid. Another significant patent is the amphotericin B/cholesterol sulfate composition and method. This composition contains particles of amphotericin B and cholesterol sulfate in a specific molar ratio. When stored in lyophilized form and reconstituted in an aqueous suspension, the particles maintain stable sizes predominantly between 50-250 nm. This formulation is noted for being significantly less toxic and more effective in treating fungal infections compared to prior amphotericin B formulations.

Career Highlights

Luke S Guo has worked with several prominent companies in the pharmaceutical industry, including Liposome Technology, Inc. and Sequus Pharmaceuticals, Inc. His experience in these organizations has allowed him to refine his expertise in drug formulation and delivery systems.

Collaborations

Throughout his career, Guo has collaborated with esteemed colleagues such as Ramachandran Radhakrishnan and Robert M Abra. These partnerships have contributed to the advancement of his research and innovations.

Conclusion

Luke S Guo's contributions to pharmaceutical innovations demonstrate his commitment to improving treatment options for bacterial and fungal infections. His patents reflect a deep understanding of drug delivery systems and their potential to enhance patient outcomes.

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