Luke Alphey

This inventor holds 14 USPTO granted patents and 7 published patent applications and 6 EPO patents. Top assignees: Oxitec Limited, Isis Innovation Limited. Active years: 2011-2023.

USPTO Granted Patents = 14 (Patent Applications = 7)

% Patents Active = 78.6

EPO Patents = 6 (Patent Applications = 6)

Average Co-Inventor Count = 1.3

ph-index = 7

Forward Citations = 200(Granted Patents)

Location History:

Abingdon, GB (2011 - 2023)
Pirbright, GB (2023)

Company Filing History:

Isis Innovation Limited

patents

Years Active: 2011-2023

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14 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 11827876 - Self-limiting, sex-specific gene and methods of using (2023-11-28),

2. 11737436 - Gene expression system (2023-08-29),

3. 10941416 - Gene expression system using alternative splicing in insects (2021-03-09),

4. 10844402 - Expression systems (2020-11-24),

5. 10426147 - Insect muscle actin promoter (2019-10-01),

6. 10059961 - Expression systems (2018-08-28),

7. 9970025 - Gene expression system using alternative splicing in insects (2018-05-15),

8. 9487801 - Biocontrol (2016-11-08),

9. 9180464 - Sorting apparatus for arthropods and method of use thereof (2015-11-10),

10. 9133477 - Expression systems (2015-09-15),

11. 9125388 - Biological control (2015-09-08),

12. 9121036 - Expression system for insect pest control (2015-09-01),

13. 8124404 - Stable integrands (2012-02-28),

14. 7998475 - Dilution of genetic traits (2011-08-16),

Title: The Innovations of Luke Alphey

Introduction

Luke Alphey is a prominent inventor based in Abingdon, GB, known for his significant contributions to the field of genetic engineering and pest control. With a total of 14 patents to his name, Alphey has made remarkable strides in developing innovative solutions for managing insect populations.

Latest Patents

Among his latest patents are groundbreaking inventions such as the self-limiting, sex-specific gene and methods of using it. This invention provides a splice control module for sex-specific splicing and expression of a gene of interest. In certain embodiments, a dsx-based splice control module is utilized to express a lethal gene in an insect, which is spliced in a sex-specific manner to impart lethality to female insects while sparing male insects. Another notable patent is the gene expression system, which features two or more conditional, dominant, lethal gene expression systems that deliver high levels of penetrance in insects. This system induces lethality at an earlier stage of development and reduces the risk of biochemical resistance compared to a single insect conditional, dominant, lethal gene expression system. These inventions are particularly useful for controlling insect populations.

Career Highlights

Throughout his career, Luke Alphey has worked with notable companies such as Oxitec Limited and Isis Innovation Limited. His work has been instrumental in advancing the field of genetic pest control, showcasing his expertise and innovative thinking.

Collaborations

Alphey has collaborated with several professionals in his field, including Martha Koukidou and Simon Warner. These collaborations have further enhanced his research and development efforts.

Conclusion

Luke Alphey's contributions to genetic engineering and pest control through his innovative patents have positioned him as a leading figure in the industry. His work continues to influence the way we approach insect population management.