Location History:
- Siena, IT (1993)
- Poggibonsi, IT (1990 - 2010)
Company Filing History:
Years Active: 1990-2010
Title: **Luciano Nencioni: An Innovator in Immunology**
Introduction
Luciano Nencioni, hailing from Poggibonsi, Italy, is a distinguished inventor known for his contributions to immunology through innovative vaccine development. With a total of five patents to his name, Nencioni has made significant strides, particularly in the creation of effective vaccines against pertussis.
Latest Patents
Among Luciano Nencioni's latest patents are groundbreaking advancements such as the development of pertussis toxin mutants. These new mutants are characterized by their immunological activity while exhibiting reduced or no toxicity. They involve the deletion and substitution of various amino acid residues in the subunit S1 amino acid sequence, making them particularly suitable for the preparation of both cellular and acellular antipertussis vaccines. Another notable patent involves the retro-inverso analogues of thymopentin, showcasing the synthesis of new analogues with immunomodulating activity. These analogues possess the potential for therapeutic applications and contribute significantly to the field of immunology.
Career Highlights
Throughout his career, Nencioni has worked with prominent companies in the pharmaceutical industry, including Sclavo Spa and Novartis AG. His expertise in vaccine research and development has positioned him as a leading figure in the field, influencing both academic and industrial advancements.
Collaborations
Luciano Nencioni has collaborated with notable colleagues, including Sabina Mariotti and Alessandro Sisto. These partnerships have facilitated innovative research and development in immunology, further enhancing the quality and efficacy of the vaccines developed through his inventions.
Conclusion
In summary, Luciano Nencioni's creative contributions and patent innovations have had a significant impact on the field of immunology, particularly in the development of vaccines against infectious diseases. His work continues to inspire advancements in the medical field, showcasing the importance of innovation in protecting public health.