Company Filing History:
Years Active: 2008-2012
Title: Innovations and Contributions of Lucia B Rothman-Denes
Introduction
Lucia B Rothman-Denes is a prominent inventor based in Chicago, IL (US). She has made significant contributions to the field of molecular biology, particularly in the development of innovative methods for RNA transcription. With a total of 3 patents, her work has broad implications for research and therapeutic applications.
Latest Patents
One of her latest patents is titled "Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences." This invention provides methods, compositions, and kits for using RNA polymerase to create transcription products that correspond to target sequences. The invention has wide applicability in research, diagnostics, and therapeutics, including the preparation of cDNA corresponding to full-length mRNA and the detection of gene-specific sequences.
Another notable patent is "Target-dependent transcription using deletion mutants of N4 RNA polymerase." This invention comprises novel methods and kits that utilize N4 vRNAP deletion mutants to detect and quantify analytes, including target nucleic acid sequences that differ by as little as one nucleotide. The method involves several processes, including annealing, DNA ligation, transcription, and optional detection.
Career Highlights
Lucia has worked with esteemed institutions such as the University of Chicago and Cellscript, LLC. Her experience in these organizations has allowed her to advance her research and contribute to significant scientific advancements.
Collaborations
Throughout her career, Lucia has collaborated with notable colleagues, including Elena K Davydova and Krystyna Maria Kazmierczak. These collaborations have further enriched her research and innovation efforts.
Conclusion
Lucia B Rothman-Denes is a distinguished inventor whose work in RNA transcription has paved the way for advancements in molecular biology. Her patents reflect her commitment to innovation and her contributions to the scientific community are invaluable.