Luca Piccoli

Title: Innovations of Luca Piccoli in Antibody Engineering

Introduction

Luca Piccoli is a notable inventor based in Bellinzona, Switzerland. He has made significant contributions to the field of biomedicine, particularly in the development of engineered antibodies. His work focuses on enhancing the functionality of antibodies, which are crucial for various therapeutic applications.

Latest Patents

Luca Piccoli holds a patent for "Antibodies with functional domains in the elbow region between variable and constant domain." This invention provides engineered antibodies and antigen binding fragments, where an additional functional domain is inserted into the elbow region of the antibody or antigen binding fragment. The patent also includes nucleic acid molecules, such as vectors, that encode these antibodies and antigen binding fragments. Furthermore, it describes host cells and compositions comprising such antibodies, antigen binding fragments, or nucleic acid molecules, along with their uses. Notably, a multispecific antibody format is provided, which allows for an additional binding site to be inserted into the elbow region of an antibody or antigen binding fragment.

Career Highlights

Luca Piccoli is affiliated with the Institute for Research in Biomedicine, where he continues to advance his research in antibody engineering. His innovative approaches have the potential to lead to new therapeutic strategies in treating various diseases.

Collaborations

Luca collaborates with Antonio Lanzavecchia, a prominent figure in the field of immunology. Their partnership enhances the research output and fosters innovative solutions in antibody development.

Conclusion

Luca Piccoli's contributions to antibody engineering exemplify the intersection of innovation and biomedicine. His patented work on engineered antibodies showcases the potential for advancements in therapeutic applications.