This inventor holds 6 USPTO granted patents and 1 published patent application and 1 EPO patent. Top assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services. Active years: 2019-2026.
Company Filing History:
Years Active: 2019-2026
Title: Innovations of Inventor Luca Gattinoni
Introduction
Luca Gattinoni is a prominent inventor based in Washington, DC, known for his significant contributions to the field of immunology. With a total of four patents to his name, Gattinoni has made remarkable strides in the development of T cell therapies.
Latest Patents
One of his latest patents involves T-cells modified to overexpress PHF19. This invention provides a mammalian T cell modified to express Phf19 at a level that exceeds that of unmodified T cells. The patent also includes a genetically-modified mammalian T cell that comprises a genetic expression vector with virally- and bacterially-derived genetic sequences, enabling the expression of Phf19 within the T cell. Additionally, Gattinoni's work encompasses pharmaceutical compositions, methods for treating diseases, and techniques for inhibiting T cell differentiation through epigenetic reprogramming. Another notable patent focuses on methods for producing T memory stem cell populations. This method involves isolating naive T cells from a mammal, activating them, and expanding their numbers in the presence of specific stimuli and inhibitors. The patent also details methods for sorting lymphocytes to create isolated T memory stem cell populations, which can be utilized in cancer treatment.
Career Highlights
Luca Gattinoni is affiliated with the National Institutes of Health, a component of the US Department of Health & Human Services. His work at this esteemed institution has allowed him to explore innovative approaches to immunotherapy and cancer treatment.
Collaborations
Gattinoni collaborates with notable colleagues, including Enrico Lugli and Mario Roederer. Their combined expertise contributes to advancing research in the field of immunology.
Conclusion
Luca Gattinoni's innovative work in T cell modification and memory stem cell production highlights his significant impact on immunotherapy. His contributions continue to pave the way for advancements in cancer treatment and disease management.