Lu Qin

Title: Innovations of Lu Qin in Retroviral Technology

Introduction

Lu Qin is a notable inventor based in Foster City, CA (US), recognized for his contributions to the field of retroviral technology. He holds a total of five patents, showcasing his innovative approach to viral production and transduction methods. His work has significant implications for gene therapy and cellular engineering.

Latest Patents

Among his latest patents is a method for the production of high titer virus and high efficiency retroviral mediated transduction of mammalian cells. This invention introduces a novel retroviral packaging system, where retroviral packaging plasmids and packagable vector transcripts are generated from high expression plasmids after stable or transient transfection in mammalian cells. The process results in high titers of recombinant retrovirus, which can transduce mammalian target cells through cocultivation or supernatant infection. The methods outlined in this patent enable the transduction of primary human cells, including T cells and human hematopoietic stem cells, with foreign genes at high efficiencies. This invention is particularly useful for the rapid production of high titer viral supernatants and for transducing cells that are typically resistant to conventional transduction methods.

Career Highlights

Lu Qin is currently employed at Cell Genesys, Inc., where he continues to advance his research in viral technologies. His innovative work has positioned him as a key figure in the development of efficient gene delivery systems.

Collaborations

He collaborates with notable colleagues, including Mitchell H. Finer and Margo R. Roberts, who contribute to the research and development efforts in his field.

Conclusion

Lu Qin's innovative contributions to retroviral technology have the potential to transform gene therapy practices. His patents reflect a commitment to advancing scientific knowledge and improving therapeutic techniques.