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Years Active: 2024-2025
Title: Innovations and Contributions of Inventor Lu Ji
Introduction
Lu Ji is a prominent inventor based in Hong Kong, China. He has made significant contributions to the field of biotechnology, particularly in the analysis of cell-free DNA. With a total of 3 patents to his name, his work has implications for disease measurement and genetic research.
Latest Patents
One of Lu Ji's latest patents focuses on fragmentation for measuring methylation and disease. This innovation involves measuring the fragmentation of cell-free DNA molecules for various purposes, including determining methylation at specific sites within a DNA molecule. The technology can be applied to biological samples such as plasma, serum, urine, and saliva. It also allows for the determination of fractional concentrations of DNA from specific tissue types and the identification of pathologies using cell-free DNA from subjects or pathogens.
Another significant patent by Lu Ji is related to determining linear and circular forms of circulating nucleic acids. This technique analyzes circular DNA in biological samples, including cell-free DNA. By employing cleaving techniques, circular DNA can be linearized for sequencing. The identification of linearized DNA molecules is achieved through various criteria, such as mapping sequences to a reference genome. This innovation enables the analysis of genetic properties and disease levels in biological samples.
Career Highlights
Lu Ji has worked with notable companies in the biotechnology sector, including Grail, Inc. and the Centre for Novostics. His experience in these organizations has contributed to his expertise in the field and has facilitated the development of his innovative patents.
Collaborations
Lu Ji has collaborated with esteemed colleagues, including Yuk-Ming Dennis Lo and Kwan Chee Chan. These partnerships have likely enhanced his research and contributed to the advancements in his work.
Conclusion
Lu Ji's contributions to the field of biotechnology through his patents and collaborations highlight his role as an influential inventor. His work in analyzing cell-free DNA has the potential to significantly impact disease measurement and genetic research.