Location History:
- Dallas, TX (US) (1994 - 1997)
- Plano, TX (US) (2009)
Company Filing History:
3 out of 5,180 
1 out of 5,445 
1 out of 5,307 
Years Active: 1994-2009
Title: Louis J Picker: Innovator in Immunology
Introduction
Louis J Picker is a distinguished inventor based in Dallas, TX (US). He has made significant contributions to the field of immunology, holding a total of 5 patents. His work focuses on advancing the understanding and assessment of T cell responses, which are crucial for immune system function.
Latest Patents
One of Picker's latest patents is a method for detecting T cell response to specific antigens in whole blood. This invention presents a novel approach to assessing antigen-specific T cells, allowing for quantification and characterization with unprecedented clarity. Importantly, this method is performed in whole blood, making it suitable for routine use in clinical immunology laboratories. The methodology enhances flow cytometric intracellular cytokine assays, enabling simultaneous measurement of multiple T cell subsets expressing various cytokines from a single whole blood culture. This approach has the advantage of evaluating T cell activation in the presence of all types of MHC autologous antigen-presenting cells found in the native sample. Additionally, it allows for a culture system that reflects systemic environmental effects on T cell responses to specific stimuli, including drugs.
Another notable patent involves the disclosure of a population of T lymphocyte precursor cells. In the bone marrow, the earliest identifiable T lymphocyte precursor is characterized as CD34.sup.+, CD7.sup.+, and Leu 8.sup.+++. The patent outlines methods for isolating these cells and their therapeutic applications.
Career Highlights
Throughout his career, Louis J Picker has worked with prominent organizations, including Becton Dickinson and Company Limited and the University of Texas System. His innovative research has significantly impacted the field of immunology and has paved the way for advancements in clinical practices.
Collaborations
Picker has collaborated with notable colleagues such as Leon W Terstappen and Jonathan W Uhr. These partnerships have contributed to the development of groundbreaking methodologies in immunological research.
Conclusion
Louis J Picker's contributions to immunology through his patents and collaborations highlight his role as a leading inventor in the field. His innovative approaches continue to influence clinical practices and enhance our understanding of immune responses.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.