Company Filing History:
Years Active: 1991-2005
Title: Louis E. Burton: Innovator in Neurotrophin Purification
Introduction
Louis E. Burton is an accomplished inventor based in San Mateo, California, who has made significant contributions to the field of neurobiology through his innovative work in the purification of neurotrophins. With a total of six patents to his name, Burton's research focuses on methods that enhance the clinical usability of neurotrophins, making strides in the development of treatments for various neurological conditions.
Latest Patents
Burton's latest patents revolve around the isolation of neurotrophins from mixtures that contain neurotrophin variants. His methods utilize hydrophobic interaction chromatography for the large-scale purification of neurotrophins, including mature nerve growth factor (NGF), which is crucial for clinical applications. These techniques offer a means to effectively separate neurotrophins from undesirable forms that may be misprocessed, misfolded, or contain varying glycosylation or charge characteristics. By providing compositions of neurotrophins that are substantially free of these variants, Burton's innovations promise to enhance the efficacy of neurotrophin-based therapies.
Career Highlights
As a member of Genentech, Inc., Burton has played a pivotal role in advancing biotechnological innovations that are vital for therapeutic development. His extensive work in neurotrophin purification reflects his commitment to improving clinical outcomes for patients with neurological disorders. Burton's patented methods underscore his expertise and ingenuity in the field, contributing to important advancements in medical research.
Collaborations
Throughout his career, Burton has collaborated with esteemed coworkers including Charles H. Schmelzer and Joanne T. Beck. These partnerships have fostered a creative environment conducive to innovation, merging talents and expertise to address complex challenges in neurobiology and biotechnology.
Conclusion
Louis E. Burton's prolific contributions to the purification of neurotrophins exemplify his dedication to advancing medical science. His patents not only represent a significant advancement in the field but also highlight the importance of innovation in developing effective clinical applications. Through his work at Genentech, Inc., Burton continues to inspire the future of neurobiological research and improve lives through his innovative spirit.