Westfield, NJ, United States of America

Louis Barash


Average Co-Inventor Count = 4.4

ph-index = 2

Forward Citations = 5(Granted Patents)


Company Filing History:


Years Active: 1983-1989

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2 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Louis Barash

Introduction: Louis Barash, a prominent inventor based in Westfield, NJ, is recognized for his significant contributions to the field of pharmaceuticals. With two patents to his name, Barash has demonstrated a strong commitment to innovation, particularly in the development of antibiotic compounds.

Latest Patents: Among Barash's notable patents is the invention of N-acyl derivatives of thienamycin. These derivatives, characterized by their structural formula, offer valuable pharmaceutical applications as antibiotics. The derivatives and their pharmaceutically acceptable salts have potential utility in treating infections, specifically when an antibiotic effect is indicated.

Additionally, Barash holds a patent for dipeptidase inhibitors. These novel chemical compounds selectively inhibit the metabolism of dipeptidase, rendering them useful in combination with antibacterial medications. The specificity of these compounds, such as Z-2-(2,2-dimethylcyclo-propanecarboxamido)-.omega.-pyridylthio-2-alkenoic acids and their analogs, showcases Barash's innovative thinking in addressing metabolic pathways relevant to antibiotic effectiveness.

Career Highlights: Louis Barash is affiliated with Merck & Company, Inc., a global leader in pharmaceutical innovation. His work at Merck not only highlights his dedication to advancing medical science but also showcases the collaborative efforts of his team in developing groundbreaking medical solutions.

Collaborations: Throughout his career, Barash has collaborated with esteemed colleagues, including Burton G. Christensen and John Hannah. Their combined expertise has contributed to the successful research and development initiatives that have led to their innovative patent filings.

Conclusion: Louis Barash stands out as a significant inventor in the pharmaceutical industry, with his patents reflecting a commitment to enhancing antibiotic therapies. His collaborative work at Merck & Company, Inc. reinforces the importance of teamwork in driving innovation and improving health outcomes.

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