Lothar J Strobl

Title: Lothar J Strobl: Innovator in Monoclonal Antibody Production

Introduction

Lothar J Strobl is a prominent inventor based in Germering, Germany. He is known for his significant contributions to the field of biotechnology, particularly in the development of human monoclonal antibodies. His innovative work has paved the way for advancements in medical research and therapeutic applications.

Latest Patents

Lothar J Strobl holds a patent titled "Process for the preparation of human monoclonal antibodies and their use." This invention provides a novel process for preparing human monoclonal antibodies from human B cells. The method involves immortalizing human antibody-producing B cells through infection with an Epstein-Barr virus that expresses Epstein-Barr virus nuclear antigen 2 (EBNA2). The EBNA2 function, essential for the immortalization process, is subsequently shut off, leading to an increase in antibody production. This invention offers various systems that enable the expression of EBNA2 function for immortalization, followed by a reduction in EBNA2 expression to enhance antibody production.

Career Highlights

Lothar J Strobl is associated with the GSF-Forschungszentrum für Umwelt und Gesundheit, GmbH, where he has made significant contributions to research and development in biotechnology. His work has been instrumental in advancing the understanding and application of monoclonal antibodies in various medical fields.

Collaborations

Throughout his career, Lothar has collaborated with notable scientists, including Georg W Bornkamm and Dirk Eick. These collaborations have further enriched his research and contributed to the advancement of knowledge in the field of immunology.

Conclusion

Lothar J Strobl's innovative work in the preparation of human monoclonal antibodies has made a lasting impact on biotechnology and medical research. His contributions continue to influence the development of therapeutic applications, showcasing the importance of innovation in science.