Company Filing History:
Years Active: 2004
Title: Lothar Brecker - Pioneer in Enzymatic Innovations
Introduction
Lothar Brecker, an esteemed inventor based in Herdecke, Germany, has made significant contributions to the field of biocatalysis through his innovative work on enzymes. With one patent to his name, he has showcased exceptional expertise in developing a novel enzyme that plays a pivotal role in organic chemistry.
Latest Patents
Brecker's noteworthy patent is centered around a unique enzyme known as 1,3-dicarbonyl-dioxygenase. This groundbreaking enzyme is capable of cleaving 1,3-dicarbonyl compounds by incorporating molecular oxygen into the substrate in amounts equimolar to the amount of substrate cleaved. The enzyme is a multimer with a molecular weight of approximately 67 kilodaltons, composed of subunits weighing around 16.6 kilodaltons. Intriguingly, nucleotide and amino acid sequence analysis of a cloned subunit revealed minimal homology with other proteins, underlining the enzyme's uniqueness. Native or recombinant versions of this enzyme hold promise for decontaminating or detoxifying acetylacetone and related diketones, offering valuable applications in chemical safety and environmental protection.
Career Highlights
Brecker’s professional journey has been marked by his association with Biocatalytics, Inc., where he has dedicated his efforts to the development of innovative biocatalytic solutions. His work not only emphasizes the potential of enzyme technologies but also highlights his commitment to advancing the field of biocatalysis.
Collaborations
Throughout his career, Lothar Brecker has collaborated with notable peers in the industry, including Grit Straganz and Anton Glieder. These collaborations have enriched his research and have contributed to the broader scientific community's understanding of enzymatic functions and applications.
Conclusion
Lothar Brecker's inventive spirit and dedication to enzyme research position him as a noteworthy figure in the realm of biocatalysis. His contributions, particularly in the development of the 1,3-dicarbonyl-dioxygenase enzyme, reflect the exciting possibilities that innovations in this field can offer for both industry and environmental sustainability.