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1 out of 832,680 Years Active: 2000-2001
Title: Lori Sussel: Innovator in Genetic Research
Introduction
Lori Sussel is a prominent inventor based in San Francisco, CA. She has made significant contributions to the field of genetic research, particularly in the study of polypeptides and transgenic mouse models. With a total of two patents to her name, Sussel's work has implications for understanding diabetes and depression.
Latest Patents
Sussel's latest patents include the invention of human Nkx-2.2 polypeptide-encoding nucleotide sequences. This invention features a human Nkx-2.2 polypeptide and nucleotide sequences that encode Nkx-2.2 polypeptides. The polynucleotide is characterized by the nucleotide sequence of SEQ ID NO:1. Additionally, the invention includes polynucleotide sequences that hybridize under stringent conditions to SEQ ID NO:1. The invention also encompasses expression vectors and host cells that comprise polynucleotides encoding a human Nkx-2.2 polypeptide. Furthermore, it relates to antibodies that specifically bind to a human Nkx-2.2 polypeptide and methods for producing these polypeptides. Another significant patent involves NKX-2.2 and NKX-6.1 transgenic mouse models for diabetes and depression. This invention features mouse models that demonstrate defects in Nkx-2.2 or Nkx-6.1 gene functions, which are crucial for insulin and serotonin production.
Career Highlights
Lori Sussel has worked at the University of California, where she has contributed to groundbreaking research in genetics. Her work has been instrumental in advancing the understanding of gene functions and their implications for various health conditions.
Collaborations
Sussel has collaborated with notable colleagues, including Michael S. German and John L. Rubenstein. These collaborations have further enriched her research and expanded the impact of her inventions.
Conclusion
Lori Sussel's innovative work in genetic research has led to significant advancements in understanding critical health issues. Her patents reflect her dedication to scientific discovery and her contributions to the field will continue to influence future research.
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