Company Filing History:
Years Active: 2015
Title: Lorenzo Menna: Innovator in Nucleoside Synthesis
Introduction
Lorenzo Menna is a notable inventor based in Milan, Italy. He has made significant contributions to the field of chemistry, particularly in the synthesis of nucleosides. His innovative work has implications for the development of antiviral and antitumor agents.
Latest Patents
Lorenzo Menna holds a patent for a process titled "Synthesis of nucleosides." This patent describes a method for preparing nucleosides, derivatives, and analogues through a coupling reaction involving a protected suitable nitrogenous purine or pyrimidine base, along with a protected suitable sugar. The process utilizes SnCl and includes the removal of SnCl4 by adding DMSO directly into the reaction mixture. This method is particularly effective for creating antiviral and antitumor agents with nucleoside-like structures, including azacytidine, decitabine, chlorfarabine, cladribine, and mizoribine. Notably, the process achieves a residual tin content lower than 300 ppm.
Career Highlights
Lorenzo Menna is currently employed at Farmabios S.p.a., where he continues to advance his research in nucleoside synthesis. His work is characterized by a commitment to innovation and excellence in the pharmaceutical field.
Collaborations
Lorenzo collaborates with esteemed colleagues, including Claudio Gianluca Pozzoli and Valentina Canevari. Their combined expertise contributes to the success of their projects and the advancement of their research.
Conclusion
Lorenzo Menna's contributions to nucleoside synthesis represent a significant advancement in the field of chemistry. His innovative processes have the potential to impact the development of important antiviral and antitumor therapies.