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Title: Long Zhao - Innovator in Viral Vector Delivery Systems
Introduction
Long Zhao is a prominent inventor based in Nanjing, China. He has made significant contributions to the field of agricultural biotechnology, particularly in the development of viral vector delivery systems for pigs. His innovative work aims to enhance vaccine delivery and efficacy in livestock.
Latest Patents
One of Long Zhao's notable patents is a viral vector delivery system designed for both the respiratory and digestive tracts of pigs. This system includes a backbone plasmid and a helper plasmid. The backbone plasmid is created by inserting a full-length cDNA of porcine enterovirus B (PEVB) into a pUC57 plasmid. The helper plasmid incorporates a green fluorescent protein-coding gene into a plasmid pCAG-T7-polymerase. This viral vector delivery system is characterized by its high efficiency in construction, rapid cytopathic effect (CPE) after cell infection, and a viral titer of up to 10TCID/mL. It also maintains high stability. A pathogenic epitope for the respiratory and digestive tracts of pigs is inserted into the backbone plasmid to produce a non-pathogenic vaccine antigen, which exhibits high stability and a significant immunization effect when inoculated in pigs. Long Zhao holds 1 patent for this innovative technology.
Career Highlights
Long Zhao has worked with esteemed organizations such as the Jiangsu Academy of Agricultural Sciences and the Snur & Db Foundation. His experience in these institutions has allowed him to advance his research and contribute to the field of agricultural sciences.
Collaborations
Throughout his career, Long Zhao has collaborated with notable colleagues, including Xing Xie and Zhixin Feng. These partnerships have facilitated the exchange of ideas and expertise, further enhancing the impact of his work.
Conclusion
Long Zhao's contributions to viral vector delivery systems represent a significant advancement in agricultural biotechnology. His innovative approach to vaccine development for pigs showcases the potential for improving livestock health and productivity.