Company Filing History:
Years Active: 1985-2001
Title: The Innovations of Lloyd H. Smith
Introduction
Lloyd H. Smith is a notable inventor based in Davis, CA (US). He holds a total of 4 patents that reflect his contributions to the field of medical diagnostics and therapeutic methods. His work primarily focuses on innovative assays and antibodies that aid in the detection and treatment of various diseases.
Latest Patents
One of his latest patents is the "High throughput papilloma virus in vitro infectivity assay." This method involves growing cells in a multi-well format, infecting them with intact virion incubated with a test agent, and measuring the expression of at least one viral nucleic acid sequence in the cells. The method also includes a control where intact virion is incubated without the test agent. The cells used are preferably human keratinocyte cells grown in monolayers, and the viral nucleic acid sequence generally comprises viral mRNA. In a preferred embodiment, the intact virion comprises Human Papilloma Virus, specifically Human Papilloma Virus-11. The measurement of expression is typically carried out by releasing the viral mRNA from the cells through lysis, amplifying the mRNA as cDNA via RT-PCR, and detecting amplicons with specific probes.
Another significant patent is related to "Adenocarcinoma antigen binding methods and reagents." This invention features a novel adenocarcinoma binding human monoclonal antibody that preferentially binds with ADCA antigens. It is useful in diagnostic and imaging methods for identifying and locating adenocarcinoma cells, as well as in therapeutic methods to reduce the reproduction of these cells. The invention encompasses the antigen, antibodies, hybridoma, reagents, therapeutic agents, and methods of use.
Career Highlights
Throughout his career, Lloyd H. Smith has made substantial contributions to the field of medical diagnostics. His innovative approaches have led to advancements in the detection and treatment of adenocarcinoma and other viral infections. His work has been recognized for its potential impact on improving patient outcomes.
Collaborations
Lloyd has collaborated with notable professionals in his field, including Nelson N. Teng and Kathleen S. Hall. These collaborations have further enhanced the development and application of his inventions.
Conclusion
Lloyd H. Smith's contributions to the field of medical diagnostics through his innovative patents demonstrate his commitment to advancing healthcare