Location History:
- Waukegan, IL (US) (1979 - 1982)
- Deerfield, IL (US) (1990 - 1998)
- Spring Grove, IL (US) (2000 - 2012)
Company Filing History:
Years Active: 1979-2012
Title: The Innovative Contributions of Lloyd Grant Simonson
Introduction
Lloyd Grant Simonson is a notable inventor based in Spring Grove, IL (US). He has made significant contributions to the field of fluorescence polarization instruments and methods for detecting biological materials. With a total of 13 patents to his name, Simonson's work has advanced the capabilities of rapid detection methods in various applications.
Latest Patents
Simonson's latest patents include groundbreaking inventions such as fluorescence polarization instruments and methods for detecting exposure to biological materials by fluorescence polarization immunoassay of saliva, oral, or bodily fluids. This inventive subject matter focuses on a method for detecting the presence of a biological substance in a test sample of saliva or oral fluid. The process involves combining the test sample with a fluorescence-labeled ligand and detecting changes in fluorescence polarization due to the binding of the ligand to the biological substance. Additionally, the method includes steps for comparing the fluorescence polarization of the test sample with that of a control solution. Simonson has also developed a miniaturized, portable apparatus for measuring fluorescence polarization in liquid samples.
Another significant patent is the rapid immunoassay of anthrax protective antigen in vaccine cultures and bodily fluids by fluorescence polarization. This competitive method estimates the concentration of proteins or antibodies, including protective antigen (PA), lethal factor (LF), and edema factor (EF). The method can detect target proteins within 5 minutes and within a concentration range of 0.1 to 10.0 nM. These methods enable rapid detection and quantitation of bacteria, bacterial antigens, or antibodies in culture media.
Career Highlights
Simonson works for the United States as represented by the Secretary of the Navy. His career has been marked by a commitment to innovation and the development of practical solutions for complex biological detection challenges.
Collaborations
Some of Simonson's notable coworkers include Malford E Cullum and Sylvia Zottu Schade. Their collaborative efforts have contributed to the advancement of technologies in the field of biological detection.
Conclusion
Lloyd Grant Simonson's innovative work in fluorescence polarization and biological detection methods has made a significant impact in his field. His contributions continue to enhance the capabilities of rapid detection technologies, showcasing the importance of innovation in addressing complex scientific challenges.
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