Location History:
- Muncie, IN (US) (2012)
- Houston, TX (US) (2012 - 2021)
Company Filing History:
Years Active: 2012-2021
Title: The Innovative Contributions of Lixin Zhang
Introduction
Lixin Zhang is a prominent inventor based in Houston, TX, known for his significant contributions to the field of immunology and vaccine development. With a total of five patents to his name, Zhang has made strides in creating innovative solutions for generating immune responses against various antigens, particularly in the context of cancer and viral infections.
Latest Patents
Zhang's latest patents include an adenoviral vector vaccine designed to elicit an immune response to specific antigens. This invention features adenoviral vectors that comprise a transcription unit encoding a secretable polypeptide. The polypeptide includes a secretory signal sequence upstream of a tumor antigen and CD40 ligand, which is modified to be secretable by removing its transmembrane domain. The methods outlined in this patent detail how to generate an immune response against cells expressing tumor antigens and how to provide long-term immunity against infections such as human papillomavirus (HPV) by administering the vector encoding the E6 or E7 protein of HPV.
Another notable patent by Zhang is the adenoviral expression vector encoding a CD40L fusion protein, which shares similar features and applications as his previous invention. This work emphasizes the potential for long-lasting immunity against cancer and viral infections through innovative vector design.
Career Highlights
Zhang's career is marked by his dedication to advancing vaccine technology and immunotherapy. His work at Vaxum, LLC has positioned him at the forefront of research aimed at combating cancer and infectious diseases. His innovative approaches have garnered attention in the scientific community, contributing to the ongoing development of effective therapeutic strategies.
Collaborations
Zhang has collaborated with notable professionals in his field, including Albert B. Deisseroth. These collaborations have further enriched his research and development efforts, leading to groundbreaking advancements in vaccine technology.
Conclusion
Lixin Zhang's contributions to the field of immunology through his innovative patents and collaborative efforts highlight his role as a leading inventor in vaccine development. His work continues to pave the way for new therapeutic approaches to combat cancer and viral infections.