Lisa V Goodrich

Title: Lisa V Goodrich: Innovator in Cancer Research

Introduction

Lisa V Goodrich is a prominent inventor based in Menlo Park, CA (US). She has made significant contributions to the field of cancer research, particularly through her innovative work on patched polypeptides. With a total of 11 patents, her research has implications for understanding and treating various forms of cancer.

Latest Patents

One of her latest patents focuses on "Patched polypeptides and uses related thereto." This patent outlines methods for isolating patched genes, including those from mouse and human sources, as well as invertebrate patched genes and sequences. The research indicates that decreased expression of patched is associated with the occurrence of human cancers, particularly basal cell carcinomas of the skin. The patched and hedgehog genes are instrumental in creating transgenic animal models for these human cancers. Additionally, the patched nucleic acid compositions are useful for identifying homologous or related proteins and the DNA sequences encoding such proteins. They also play a role in producing compositions that modulate the expression or function of the protein and in studying associated physiological pathways. Furthermore, modulation of gene activity in vivo is utilized for prophylactic and therapeutic purposes, including cancer treatment and identification of cell types based on expression. The DNA is also employed as a diagnostic tool for genetic predisposition to cancer and for identifying specific cancers with mutations in this gene.

Career Highlights

Throughout her career, Lisa has worked with esteemed institutions such as Leland Stanford Junior University and the University of California. Her research has not only advanced scientific understanding but has also paved the way for potential therapeutic applications in oncology.

Collaborations

Some of her notable coworkers include Matthew Peter Scott and Ronald L Johnson. Their collaborative efforts have contributed to the advancement of research in the field of cancer genetics.

Conclusion

Lisa V Goodrich's innovative work in cancer research exemplifies the impact of scientific inquiry on health and medicine. Her patents and research continue to influence the understanding and treatment of cancer, showcasing her role as a leading inventor in this critical field.