Company Filing History:
2 out of 410 
1 out of 832,843 Years Active: 2000-2002
Title: Innovations by Lisa S Nelson
Introduction
Lisa S Nelson is an accomplished inventor based in DeForest, WI (US). She has made significant contributions to the field of nucleic acid detection, holding a total of 3 patents. Her work has advanced the methods and technologies used in biological sample analysis.
Latest Patents
One of her notable inventions is a system for nucleic acid detection. This invention discloses methods, compositions, and kits for detecting extremely low levels of nucleic acid, cells, and cellular material in biological samples. The nucleic acid detection systems utilize either the pyrophosphorolysis reaction catalyzed by various polymerases or nuclease digestion coupled with pyrophosphorylation catalyzed by phosphoribosylpyrophosphate synthetase. This process produces either deoxyribonucleoside triphosphates or ribonucleoside triphosphates. The dNTPs are transformed to ATP by the action of nucleoside diphosphate kinase. The ATP produced by these reactions may be detected by luciferase or NADH-based detection systems. If more sensitive detection is required, schemes for the amplification of NTPs and dNTPs are provided. Additionally, a detection system for cells or cellular material in a sample is provided, wherein AMP and a high-energy phosphate donor added to a sample are converted to ATP by the action of endogenous enzymes, followed by detection of the ATP.
Career Highlights
Throughout her career, Lisa has worked with prominent organizations, including Promega Corporation. Her innovative approaches have significantly impacted the field of molecular biology and diagnostics.
Collaborations
Lisa has collaborated with notable colleagues such as John William Shultz and Donna M Leippe. These partnerships have fostered advancements in her research and development efforts.
Conclusion
Lisa S Nelson's contributions to nucleic acid detection exemplify her dedication to innovation in the scientific community. Her patents and collaborations continue to influence the field and pave the way for future advancements.