Ling Hong Xie

Title: Innovations of Ling Hong Xie

Introduction

Ling Hong Xie is a notable inventor based in Guilford, CT (US). He has made significant contributions to the field of pharmaceuticals, particularly in the development of compounds that target central nervous system (CNS) diseases. With a total of 3 patents to his name, Xie's work is recognized for its potential therapeutic applications.

Latest Patents

One of Xie's latest patents involves benzimidazole and pyridylimidazole derivatives. This invention relates to benzimidazoles, pyridylimidazoles, and related bicyclic heteroaryl compounds, all of which may be described by Formula I. The invention is particularly focused on compounds that bind with high selectivity and high affinity to the benzodiazepine site of GABA receptors. Additionally, this invention encompasses pharmaceutical compositions comprising such compounds and their use in treating certain CNS diseases. Novel processes for preparing compounds of Formula I are also disclosed. Furthermore, the invention discusses the use of these compounds in combination with other CNS agents to enhance their effects. It also relates to the use of these compounds as probes for the localization of GABA receptors in tissue sections.

Career Highlights

Ling Hong Xie is currently associated with Neurogen Corporation, where he continues to innovate in the pharmaceutical sector. His work has the potential to impact the treatment of various CNS disorders significantly.

Collaborations

Xie collaborates with talented individuals such as Guiying Li and Pamela Ann Albaugh, who contribute to the research and development efforts at Neurogen Corporation.

Conclusion

Ling Hong Xie's contributions to the field of pharmaceuticals, particularly through his innovative patents, highlight his role as a key inventor in the development of treatments for CNS diseases. His ongoing work promises to advance therapeutic options for patients in need.