Limin Zeng

Title: Innovations of Limin Zeng in Pharmaceutical Chemistry

Introduction

Limin Zeng is a prominent inventor based in Shanghai, China, known for his significant contributions to pharmaceutical chemistry. He has been instrumental in developing innovative compounds that target viral infections and cancer treatment. With a total of two patents to his name, Zeng's work showcases his dedication to advancing medical science.

Latest Patents

Zeng's latest patents include a phthalazinone compound and an o-aminoheteroaryl alkynyl-containing compound. The phthalazinone compound is designed to inhibit the replication of viruses, particularly targeting the viral nucleocapsid. This compound demonstrates potent activity against HBV DNA replication and shows promising liver targeting capabilities. The second patent, concerning the o-aminoheteroaryl alkynyl-containing compound, reveals its high inhibitory activity against FGFR and RET, making it effective in treating human lung and gastric cancer cell lines. Pharmacokinetic data indicates that this compound has favorable druggability and exhibits significant tumor growth inhibition in long-term animal models.

Career Highlights

Limin Zeng is affiliated with the Chinese Academy of Sciences, where he conducts his research and development. His work has garnered attention for its potential impact on treating viral infections and various cancers. Zeng's innovative approach to drug development emphasizes the importance of targeting specific biological pathways to enhance therapeutic efficacy.

Collaborations

Zeng collaborates with notable colleagues, including Youhong Hu and Jianping Zuo, who contribute to his research endeavors. Their combined expertise fosters a collaborative environment that enhances the quality and scope of their scientific investigations.

Conclusion

Limin Zeng's contributions to pharmaceutical chemistry through his innovative patents highlight his role as a leading inventor in the field. His work not only advances medical science but also offers hope for effective treatments against viral infections and cancer.