Location History:
- Lexington, KY (US) (2011 - 2015)
- Raleigh, NC (US) (2012 - 2023)
Company Filing History:
13 out of 1,440 
13 out of 882 
Years Active: 2011-2023
Title: Inventor Profile: Lily Gavilano
Introduction
Lily Gavilano is a notable inventor based in Raleigh, North Carolina. With a total of 13 patents to her name, she has made significant contributions to the field of biotechnology and tobacco research. Her work focuses on modifying tobacco alkaloid content through innovative genetic methods, with an aim to reduce the harmful effects of tobacco consumption.
Latest Patents
One of Gavilano's most recent patents is centered on the alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes. This patent outlines compositions and methods for reducing the levels of nornicotine and its carcinogenic metabolite, N'-nitrosonornicotine (NNN), in tobacco plants and their parts. The compositions include isolated polynucleotides and polypeptides linked to cytochrome P450s, which are crucial for the metabolic conversion of nicotine to nornicotine in these plants. This innovative approach provides expression cassettes, vectors, and methods designed to inhibit the function of cytochrome P450 polypeptides, thereby lowering the carcinogenic potential of tobacco products and secondary smoke exposure.
Career Highlights
Throughout her career, Lily Gavilano has been affiliated with reputable institutions such as North Carolina State University and the University of Kentucky Research Foundation. Her work at these institutions has laid the groundwork for her groundbreaking patents and has positioned her as a leader in her field.
Collaborations
Lily has collaborated with esteemed colleagues Ralph E Dewey and Steven W Bowen, contributing to the research and development of innovative solutions for tobacco product safety. These collaborations have not only enriched her work but have also enhanced the overall impact of her inventions.
Conclusion
Lily Gavilano's contributions to the field of tobacco research through her inventive patents and collaborations mark her as a forward-thinking inventor. Her commitment to reducing the health risks associated with tobacco use showcases the importance of innovation in addressing public health concerns.