Company Filing History:
Years Active: 2025
Title: Lijuan Wen: Innovator in Blood-Brain Barrier Research
Introduction
Lijuan Wen is a prominent inventor based in Hangzhou, China. He has made significant contributions to the field of biomedical research, particularly in the development of blood-brain barrier permeability regulators. With a total of 2 patents, his work focuses on innovative solutions for enhancing drug delivery to the brain.
Latest Patents
Lijuan Wen's latest patents include groundbreaking inventions that utilize Axitinib and its analogs. The first patent describes the use of Axitinib in preparing a blood-brain barrier permeability regulator. This invention aims to reduce blood-brain barrier permeability and promote recovery from pathological states. The mechanism involves inhibiting the vascular endothelial cell growth factor signaling pathway, which helps maintain the integrity of tight junction proteins like Claudin-5 and Occludin.
The second patent involves the use of SC79 or its analogs in creating a blood-brain barrier permeability regulator. This invention enhances the transportation efficiency of brain-targeting drug delivery systems, particularly an Angiopep-2-modified glycolipid nano-delivery system. By activating the Claudin-5 and Occludin signaling pathways, this regulator improves therapeutic efficacy in treating conditions related to blood-brain barrier permeability changes.
Career Highlights
Lijuan Wen is affiliated with Zhejiang University, where he conducts his research and development activities. His work has garnered attention for its potential to revolutionize treatments for neurological diseases by improving drug delivery mechanisms.
Collaborations
Lijuan collaborates with notable colleagues, including Fuqiang Hu and Hong Yuan, who contribute to his research endeavors. Their combined expertise enhances the innovative potential of their projects.
Conclusion
Lijuan Wen's contributions to blood-brain barrier research exemplify the impact of innovative thinking in biomedical science. His patents represent significant advancements in drug delivery systems, promising improved therapeutic outcomes for patients.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.