This inventor holds 2 USPTO granted patents. Top assignee: Columbia University. Active years: 2011-2020.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Scarsdale, NY (US) (2011)
- New York, NY (US) (2020)
Company Filing History:
Years Active: 2011-2020
Title: Innovations of Liang Tong in Viral Production and Acetyl-CoA Carboxylase
Introduction
Liang Tong is a notable inventor based in New York, NY (US). He has made significant contributions to the fields of viral production and enzymatic activity modulation. With a total of 2 patents, his work has implications in various biotechnological applications.
Latest Patents
One of Liang Tong's latest patents is a method for significantly increasing lentiviral production. This invention focuses on enhancing viral particle maturation and production by inhibiting Heme Oxygenase 2 (HO-2) from binding to the group-specific antigen (Gag) of viral proteins. By allowing the delivery of viral proteins to plasma membranes, replication and maturation can occur without interference from HO-2. This method is particularly applicable to the production of lentiviruses from viral proteins where the Matrix domain (MA) of the Gag is myristoylated.
Another significant patent involves the carboxyltransferase domain of acetyl-CoA carboxylase. This invention provides compositions and crystals of the carboxyltransferase (CT) domain of various acetyl-CoA carboxylase (ACC) proteins. It also outlines methods for identifying and designing compounds that can modulate ACC activity, based on the X-ray crystallographic structures of the CT domain. This work has potential applications in designing anti-obesity, anti-diabetes, antibiotic, and herbicide compounds.
Career Highlights
Liang Tong is affiliated with Columbia University, where he continues to advance research in his fields of expertise. His innovative approaches have garnered attention and recognition within the scientific community.
Collaborations
Liang has collaborated with esteemed colleagues such as Stephen P. Goff and Yiping Zhu, contributing to the advancement of research in viral production and enzymatic functions.
Conclusion
Liang Tong's contributions to the fields of viral production and enzymatic activity are noteworthy. His patents reflect a commitment to innovation and the potential for significant advancements in biotechnology.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile