This inventor holds 1 USPTO granted patent. Top assignee: Leland Stanford Junior University. Active years: 2017.
Company Filing History:
Years Active: 2017
Title: Innovations of Lia E Gracey Maniar
Introduction
Lia E Gracey Maniar is a prominent inventor based in Menlo Park, CA (US). She has made significant contributions to the field of genetic engineering, particularly in the area of transgene expression. Her work has implications for various applications in biotechnology and medicine.
Latest Patents
Lia holds a patent titled "Nucleosome-excluding sequences (NES) as a DNA spacer in vectors results in prolonged transgene expression in eukaryotic cells." This innovative patent addresses the silencing effect of spacer sequences, such as bacterial backbone sequences in plasmids or other episomal vectors. By engineering the spacer to include nucleosome exclusion sequences, she has found a way to reverse this silencing effect, thereby enhancing transgene expression.
Career Highlights
Lia is affiliated with Leland Stanford Junior University, where she continues her research and development in genetic engineering. Her work has garnered attention for its potential to improve the efficacy of gene therapies and other biotechnological applications.
Collaborations
Lia has collaborated with notable colleagues, including Jiamiao Lu and Andrew Fire, who have contributed to her research endeavors. Their combined expertise has further advanced the understanding of transgene expression and its regulation.
Conclusion
Lia E Gracey Maniar is a trailblazer in the field of genetic engineering, with her innovative patent paving the way for advancements in transgene expression. Her contributions to biotechnology are significant and continue to influence the industry.