Eagleville, PA, United States of America

Li Shi


Average Co-Inventor Count = 3.0

ph-index = 3

Forward Citations = 59(Granted Patents)


Company Filing History:


Years Active: 2001-2002

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3 patents (USPTO):Explore Patents

Title: **Innovator Li Shi: Pioneering HPV Formulations in Eagleville, PA**

Introduction

Li Shi, based in Eagleville, Pennsylvania, is a remarkable inventor with a focus on advancing medical formulations. With a portfolio of three patents, she continues to contribute significantly to the field of virology, particularly in the development of human papillomavirus (HPV) vaccines and formulations.

Latest Patents

Li's recent contributions include two groundbreaking patents focused on HPV. The first patent details **Stabilized Human Papillomavirus Formulations**, which disclose formulations that prevent protein aggregation and offer prolonged stability as aqueous solutions. These formulations incorporate salts like sodium chloride and non-ionic surfactants such as Polysorbate 80 (Tween 80®) in physiologically acceptable concentrations. The second patent, **Human Papillomavirus Vaccine Formulations**, describes new vaccine compositions exhibiting enhanced long-term stability. Key components of these formulations include virus-like particles (VLPs) absorbed onto aluminum, along with necessary salts, non-ionic surfactants, and buffers. Additionally, some formulations utilize a polymeric polyanionic stabilizer to further enhance efficacy.

Career Highlights

Li Shi is currently affiliated with Merck & Company, Inc., where her research and innovation efforts are focused on improving health outcomes through effective vaccine development. Her projects underline her dedication to enhancing vaccine formulations and addressing the challenges posed by HPV.

Collaborations

Throughout her career, Li has collaborated with renowned colleagues including David B. Volkin and Henryk Mach, leveraging their expertise to enhance her research and innovation initiatives. These collaborations have played a crucial role in her successful patent acquisitions and developments.

Conclusion

Li Shi stands out as an influential inventor in the healthcare sector, specifically in the realm of HPV prevention. Her patented inventions reflect not only her innovative spirit but also a commitment to improving public health through scientific advancements. As she continues her work at Merck & Company, Inc., the future promises to be bright for her contributions to vaccination technology and virology.

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